Cefcanel
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Cefcanel
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CAS No:
41952-52-7
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Formula:
C19H18N4O5S3
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Chemical Name:
Cefcanel
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Synonyms:
Cefcanel;(6R)-7β-[[(R)-Hydroxyphenylacetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;ALL-103;KY-087
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CAS No:
Description
Cefcanel is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcanel binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Drug Information
3-(2-(5-methyl-1,3,4-thiadiazyl)mercaptomethyl)-7-(D-(-)-mandelamido)-3-cephem-4-carboxylic acid
Computed Properties
Molecular Weight:478.6
XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:478.04393321
Monoisotopic Mass:478.04393321
Topological Polar Surface Area:212
Heavy Atom Count:31
Complexity:776
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes