Cefadroxil Hemihydrate

Cefadroxil Hemihydrate is the hemihydrate form of cefadroxil, a semi-synthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cefadroxil hemihydrate binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Molecular Weight:744.8
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:744.18834833
Monoisotopic Mass:744.18834833
Topological Polar Surface Area:318
Heavy Atom Count:51
Complexity:629
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes