2-Chloro-8-methylquinoline
-
2-Chloro-8-methylquinoline
structure -
-
CAS No:
4225-85-8
-
Formula:
C10H8ClN
-
Chemical Name:
2-Chloro-8-methylquinoline
-
Synonyms:
2-CHLORO-8-METHYLQUINOLINE;2-CHLORO-8-METHYL-QUINOLINE;ACMC-209joo;SCHEMBL2133770;CTK4I5949;DTXSID40615753;KS-00000Q1I;ANW-29782;ZINC26474739;AKOS013465676
-
CAS No:
2-Chloro-8-methylquinoline Use and Manufacturing
General procedure: To a stirred solution of the appropriate azine N-oxides in anhydrous CHTo a solution of 8- methylquinoline 1-oxide (0.440 g, 2.764 mmol) in toluene (10 ml) was added phosphoryl trichloride (1.265 ml, 13.82 mmol), and the reaction was heated to 80 A mixture of 8-methyl-lH-quinolin-2-one (107) (580 mg, 3.6 mmol) and phosphorus oxychloride ( 5 mL) was stirred at 60°C overnight. The mixture was then poured onto ice water and extracted with DCM (3x 50 mL). The combined extracts were washed with water (2x100 mL) and dried with Na