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Home > Encyclopedia > 2-chloro-3-nitro-6-hydroxypyridine

2-chloro-3-nitro-6-hydroxypyridine

2-chloro-3-nitro-6-hydroxypyridine structure

2-chloro-3-nitro-6-hydroxypyridine 

structure
  • CAS No:

    198268-98-3

  • Formula:

    C5H3ClN2O3

  • Chemical Name:

    2-chloro-3-nitro-6-hydroxypyridine

  • Synonyms:

    2-chloro-3-nitro-6-hydroxypyridine;6-chloro-5-nitropyridin-2-ol;6-Chloro-5-nitropyridin-2(1H)-one;6-Chloro-5-nitro-1H-pyridin-2-one;6-Chloro-5-nitropyridin-2(1H)

2-chloro-3-nitro-6-hydroxypyridine Basic Attributes

174.54192

173.983215

DTXSID10855866

2933399090

Characteristics

74.9

0.6

1.6±0.1 g/cm3

126.4±27.3 °C

1.603

Safety Information

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

2-chloro-3-nitro-6-hydroxypyridine Use and Manufacturing

A suspension of 2-chloro-6-methoxy-3-nitropyridine (20.85 g, 110.57 mmol) in concentrated hydrochloric acid (37percent) (171 mL, 5528.49 mmol) was stirred at 90 A mixture of 2-chloro-6-methoxy-3-nitropyridine (5 g, 10.61 mmol) in HCl solution (12 M, 60 mL) was stirred at 90° C. for 16 h. Then the reaction mixture was neutralized with NaOH carefully and extracted with EtOAc (100 mL*2). The organic phases were combined, washed with brine and dried over Na

Computed Properties

Molecular Weight:174.54
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:173.9832197
Monoisotopic Mass:173.9832197
Topological Polar Surface Area:74.9
Heavy Atom Count:11
Complexity:276
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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