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CHLOROTOXIN

CHLOROTOXIN structure

CAS No:
163515-35-3
Formula:
C158H256N52O48S11
Chemical Name:
CHLOROTOXIN
Synonyms:
CHLOROTOXIN;CLTX;CLTX (EGYPTIAN SCORPION);H-MET-CYS-MET-PRO-CYS-PHE-THR-THR-ASP-HIS-GLN-MET-ALA-ARG-LYS-CYS-ASP-ASP-CYS-CYS-GLY-GLY-LYS-GLY-ARG-GLY-LYS-CYS-TYR-GLY-PRO-GLN-CYS-LEU-CYS-ARG-NH2;H-MET-CYS-MET-PRO-CYS-PHE-THR-THR-ASP-HIS-GLN-MET-ALA-ARG-LYS-CYS-ASP-ASP-CYS-CYS-GLY-GLY-LYS-GLY-ARG-GLY-LYS-CYS-TYR-GLY-PRO-GLN-CYS-LEU-CYS-ARG-NH2, (DISULFIDE BONDS BETWEEN CYS2 AND CYS19/CYS5 AND CYS28/CYS16 AND CYS33/CYS20 AND CYS35);H-MET-CYS-MET-PRO-CYS-PHE-THR-THR-ASP-HIS-GLN-MET-ALA-ARG-LYS-CYS-ASP-ASP-CYS-CYS-GLY-GLY-LYS-GLY-ARG-GLY-LYS-CYS-TYR-GLY-PRO-GLN-CYS-LEU-CYS-ARG-OH;MET-CYS-MET-PRO-CYS-PHE-THR-THR-ASP-HIS-GLN-MET-ALA-ARG-LYS-CYS-ASP-ASP-CYS-CYS-GLY-GLY-LYS-GLY-ARG-GLY-LYS-CYS-TYR-GLY-PRO-GLN-CYS-LEU-CYS-ARG-NH2;CHLOROTOXIN, RECOMBINANT, EXPRESSED
Categories:
Biochemical Engineering > Polypeptide

Description

Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.

CHLOROTOXIN Basic Attributes

Molecular Weight：

4004.76

Exact Mass：

3992.50000

Characteristics

PSA：

2001.75000

XLogP3：

-22

Appearance：

lyophilized powder

Water Solubility：

aqueous buffer: soluble

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

Drug Information

MeSH：

Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept. (See all compounds classified as Neurotoxins.)

MeSH Entry Terms：

131I-TM-601

CHLOROTOXIN Use and Manufacturing

Biochemical probe for voltage-gated chloride channels.

Computed Properties

Molecular Weight:3996
XLogP3:-22
Hydrogen Bond Donor Count:56
Hydrogen Bond Acceptor Count:66
Rotatable Bond Count:63
Exact Mass:3993.5684800
Monoisotopic Mass:3992.5651252
Topological Polar Surface Area:1900
Heavy Atom Count:269
Complexity:9210
Defined Atom Stereocenter Count:33
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of CHLOROTOXIN

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

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Chlorotoxin,Cltx (Egyptian scorpion)

CAS No.: 163515-35-3

Grade: Pharmaceutical Grade

Content: 99%

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Guide of CHLOROTOXIN

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
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CHLOROTOXIN

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