Cicletanine
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Cicletanine
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CAS No:
89943-82-8
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Formula:
C14H12ClNO2
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Chemical Name:
Cicletanine
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Synonyms:
Furo[3,4-c]pyridin-7-ol,3-(4-chlorophenyl)-1,3-dihydro-6-methyl-;Furo[3,4-c]pyridin-7-ol,3-(4-chlorophenyl)-1,3-dihydro-6-methyl-,(±)-;3-(4-Chlorophenyl)-1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol;Cycletanide;Cicletanine;(±)-Cicletanine;Win 90000;Cicletanide;87520-10-3;92134-72-0
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CAS No:
Description
Cicletanine is an organochlorine compound.|Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
Safety Information
P280, P305+P351+P338, P310
H318
|Danger|H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]|P280, P305+P351+P338, and P310|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
1,3-dihydro-6-methyl-7-hydroxy-3-(4-chlorophenyl)furo(3,4-d)pyridine
Computed Properties
Molecular Weight:261.70
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:261.0556563
Monoisotopic Mass:261.0556563
Topological Polar Surface Area:42.4
Heavy Atom Count:18
Complexity:294
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes