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Cilofungin

Cilofungin structure

Cilofungin 

structure
  • CAS No:

    79404-91-4

  • Formula:

    C49H71N7O17

  • Chemical Name:

    Cilofungin

  • Synonyms:

    Cyclo[L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-];Cyclo[L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]-[(4R,5R)-4,5-dihydroxy-N2-[4-(octyloxy)benzoyl]-L-Orn*-]-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]];LY-121019;Cilofungin;(4R,5R)-N2-[4-(Octyloxy)benzoyl]-4,5-dihydroxycyclo[L-Orn*-L-Thr-L-t4Hyp-[(3S,4S)-3,4-dihydroxy-4-(4-hydroxyphenyl)-L-Abu-]-L-Thr-[(3S,4S)-3-hydroxy-4-methyl-L-Pro-]];Antibiotic LY-121019

Description

ChEBI: A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycoti agent against Candida albicans.

Cilofungin Basic Attributes

1030.13

1029.49000

Characteristics

391.38000

-1.72050

1.46g/cm3

1397ºC at 760 mmHg

798.7ºC

1.654

Cilofungin Use and Manufacturing

Antifunga.

Computed Properties

Molecular Weight:1030.1
XLogP3:0.7
Hydrogen Bond Donor Count:14
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:15
Exact Mass:1029.49064382
Monoisotopic Mass:1029.49064382
Topological Polar Surface Area:377
Heavy Atom Count:73
Complexity:1870
Defined Atom Stereocenter Count:7
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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