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Co102862

Co102862 structure

CAS No:
181144-66-1
Formula:
C14H12FN3O2
Chemical Name:
Co102862
Synonyms:
Co102862;2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide;(E)-2-(4-(4-fluorophenoxy)benz-ylidene)hydrazinecarboxaMide;[(E)-[4-(4-fluorophenoxy)phenyl]methyleneamino]urea
Categories:
Organic Chemistry > Semicarbazides

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Description

[[4-(4-fluorophenoxy)phenyl]methylideneamino]urea is an aromatic ether.

Co102862 Basic Attributes

Molecular Weight：

273.266

Exact Mass：

273.09135480

UNII：

0KN11H90GF

DSSTox ID：

DTXSID70171079

Characteristics

Storage Conditions：

Store at RT

Drug Information

MeSH Entry Terms：

4-(4-fluorophenoxy)benzaldehyde semicarbazone

Co102862 Use and Manufacturing

Broad spectrum, state-dependent blocker of voltage-gated sodium channels. Displays ~ 80-fold higher affinity for inactivated Na + channels compared to channels in the resting state. Anticonvulsant; displays activity in rodent models of tonic/clonic and partial-complex seizures.

Computed Properties

Molecular Weight:273.26
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:273.09135480
Monoisotopic Mass:273.09135480
Topological Polar Surface Area:76.7
Heavy Atom Count:20
Complexity:335
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes