5-Chloro-2-indanone
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5-Chloro-2-indanone
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CAS No:
74444-81-8
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Formula:
C9H7ClO
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Chemical Name:
5-Chloro-2-indanone
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Synonyms:
5-Chloro-2-indanone;5-Chloro-1H-inden-2(3H)-one;5-Chloro-indan-2-one;2H-Inden-2-one, 5-chloro-1,3-dihydro-
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CAS No:
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
5-Chloro-2-indanone Use and Manufacturing
Step 1 To a stirred solution of oxindole 1 (4.19 g, 25 mmol) in methanol (50 mL) was added aldehyde 2 (3.96 g, 25 mmol) and piperidine (2.45 mL, 25 mmol). The reaction mixture was stirred at room temperature for 3 h and the yellow precipitate was collected, washed successively with methanol, hexanes, and ethyl ether and dried to give compound 3 (6.25 g, 81% yield).