Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > 3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE

3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE

3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE structure

3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE 

structure
  • CAS No:

    914225-61-9

  • Formula:

    C7H4ClF4N

  • Chemical Name:

    3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE

  • Synonyms:

    3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE;3-Chloro-4-fluoro-5-(trifluoromethyl)

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE Basic Attributes

213.5599728

212.996841

DTXSID30652293

Characteristics

26

2.9

1.5±0.1 g/cm3

235.7±40.0°C at 760 mmHg

96.4±27.3 °C

1.483

3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE Use and Manufacturing

In a 100 mL round-bottomed flask, di(lH-imidazol-l-yl)methanethione (1.25 g, 7.02 mmol, Eq: 1.5) was combined with CH2CI2 (30 mL) to give a colorless solution. 3-chloro-4- fluoro-5-(trifluoromethyl)aniline (lg, 4.68 mmol, Eq: 1.00) in CH2CI2 (20 mL) was added dropwise at 0C. The reaction was allowed to warm to room temperature, and allowed to stir overnight. Concentrate the solution, the compound was isolated by column chromatography (CH2C12/Hexanes = 80/20) to give the product 0.8 g (67%).

Computed Properties

Molecular Weight:213.56
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Exact Mass:212.9968395
Monoisotopic Mass:212.9968395
Topological Polar Surface Area:26
Heavy Atom Count:13
Complexity:184
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.