3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE
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3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE
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CAS No:
914225-61-9
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Formula:
C7H4ClF4N
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Chemical Name:
3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE
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Synonyms:
3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE;3-Chloro-4-fluoro-5-(trifluoromethyl)
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CAS No:
3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE Use and Manufacturing
In a 100 mL round-bottomed flask, di(lH-imidazol-l-yl)methanethione (1.25 g, 7.02 mmol, Eq: 1.5) was combined with CH2CI2 (30 mL) to give a colorless solution. 3-chloro-4- fluoro-5-(trifluoromethyl)aniline (lg, 4.68 mmol, Eq: 1.00) in CH2CI2 (20 mL) was added dropwise at 0C. The reaction was allowed to warm to room temperature, and allowed to stir overnight. Concentrate the solution, the compound was isolated by column chromatography (CH2C12/Hexanes = 80/20) to give the product 0.8 g (67%).
Computed Properties
Molecular Weight:213.56
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Exact Mass:212.9968395
Monoisotopic Mass:212.9968395
Topological Polar Surface Area:26
Heavy Atom Count:13
Complexity:184
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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3-CHLORO-4-FLUORO-5-(TRIFLUOROMETHYL)ANILINE
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