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CP 376395

CP 376395 structure

CAS No:
175140-00-8
Formula:
C21H30N2O.ClH
Chemical Name:
CP 376395
Synonyms:
CP 376395;CP 376395 hydrochloride;N-(1-Ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-4-pyridinaminehydrochloride
Categories:
Organic Chemistry > Amides

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CP 376395 Basic Attributes

Molecular Weight：

362.942

Exact Mass：

326.236

UNII：

5113G7FP34

DSSTox ID：

DTXSID0047298

Characteristics

PSA：

34.2

XLogP3：

6.4

Storage Conditions：

Desiccate at RT

Drug Information

MeSH Entry Terms：

(3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine

CP 376395 Use and Manufacturing

Potent and selective CRF 1 receptor antagonist (K i values are 12 and >10000 nM for CRF 1 and CRF 2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.

Computed Properties

Molecular Weight:326.5
XLogP3:6.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:326.235813585
Monoisotopic Mass:326.235813585
Topological Polar Surface Area:34.2
Heavy Atom Count:24
Complexity:359
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes