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COELENTERAZINE H

COELENTERAZINE H structure

CAS No:
50909-86-9
Formula:
C26H21N3O2
Chemical Name:
COELENTERAZINE H
Synonyms:
Renilla Luciferin;H-coelenterazine;2-Deoxycoelenterazine Luciferin (Renilla);Colenterazine H;2,8-dibenzyl-6-(4-hydroxyphenyl)iMidazo[1,2-a]pyrazin-3(7H)-one;CLZN h [Coelenterazine h];CLZ-H;CLZN-H

Description

Coelenterazine h is a derivative of Coelenterazine. Coelenterazine h is more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.

Renilla luciferin is a member of phenols and an imidazopyrazine. It has a role as a luciferin. It derives from a hydride of an imidazo[1,2-a]pyrazine.

Coelenterazine-h (50909-86-9) may be used as a substrate in gene reporter assays, live cell assays, and biochemical assays (ELISA, BRET etc). Renilla luciferase catalyzes coelenterazine oxidation by oxygen to produce light. Coelenterazine-h produces 10-fold higher light output than native coelenterazine. Coelenterazine-h also undergoes autoluminescence, which is enhanced by superoxide anion and peroxynitrite in cells.

Coelenterazine is an imidazopyrazinone derivative. It is a substrate for bioluminescence in many luminous marine organisms.

COELENTERAZINE H Basic Attributes

Molecular Weight：

407.46

Exact Mass：

407.46

UNII：

W6HKC9Y0YK

DSSTox ID：

DTXSID00376393

Color/Form：

Yellow

HScode：

2933998090

Characteristics

λmax：

437nm

PSA：

64.9

XLogP3：

4.60

Appearance：

Yellow solid

Density：

1.26±0.1 g/cm3(Predicted)

Melting Point：

>200℃

Boiling Point：

593.5±60.0 °C(Predicted)

Flash Point：

312.7±32.9 °C

Refractive Index：

1.675

Water Solubility：

soluble in methanol, ethanol

Storage Conditions：

−20°C

PKA：

10.50±0.30(Predicted)

Critical Temperature & Pressure：

-20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

36/37/38

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

COELENTERAZINE H Use and Manufacturing

Coelenterazine h, is a derivative of Coelenterazine (C636000), and iis more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.

Computed Properties

Molecular Weight:407.5
XLogP3:5.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:407.16337692
Monoisotopic Mass:407.16337692
Topological Polar Surface Area:70.6
Heavy Atom Count:31
Complexity:555
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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141994-72-1
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102641-82-7
Azomethine H

32266-60-7
Benzoylgomisin H Formula

66056-23-3
COELENTERAZINE F Formula

123437-16-1
Cytochalasin H Formula

53760-19-3
Shizukalide H Structure

1136932-34-7
Odoroside H Structure

18810-25-8
What is H Acid disodium salt

3963-80-2
What is Bruceanol H

168569-27-5

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Guide of COELENTERAZINE H

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

COELENTERAZINE H

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