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CPPG

CPPG structure

CAS No:
183364-82-1
Formula:
C11H14NO5P
Chemical Name:
CPPG
Synonyms:
CPPG;(+/-)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;(RS)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;(RS)-CPPG;(RS)-α-Cyclopropyl-4-phosphonophenylglycine

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Description

2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.

CPPG Basic Attributes

Molecular Weight：

271.21

Exact Mass：

271.061

Characteristics

PSA：

121

XLogP3：

-3.1

Appearance：

white to beige Solid

Water Solubility：

H2O: >5mg/mL

Storage Conditions：

Store at RT

Safety Information

wgk germany：

hazard class code：

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

CPPG Use and Manufacturing

Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .

Computed Properties

Molecular Weight:271.21
XLogP3:-3.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:271.06095954
Monoisotopic Mass:271.06095954
Topological Polar Surface Area:121
Heavy Atom Count:18
Complexity:383
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of CPPG

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties

CPPG

SDS

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