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Monodansylcadaverine

Monodansylcadaverine structure

CAS No:
10121-91-2
Formula:
C17H25N3O2S
Chemical Name:
Monodansylcadaverine
Synonyms:
1-Naphthalenesulfonamide,N-(5-aminopentyl)-5-(dimethylamino)-;N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide;Dansylcadaverine;Monodansylcadaverine;99473-69-5;2354406-37-2
Categories:
Organic Chemistry > Amides

Description

Dansylcadaverine is a fluorescent probe.

Monodansylcadaverine is a sulfonamide obtained by formal condensation of the sulfo group of 5-(dimethylamino)naphthalene-1-sulfonic acid with one of the amino groups of cadaverine. It has a role as a fluorochrome, a protective agent and an EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor. It is a sulfonamide, an aminonaphthalene, a tertiary amino compound and a primary amino compound. It derives from a cadaverine.

Monodansylcadaverine Basic Attributes

Molecular Weight：

335.46

Exact Mass：

335.46

EC Number：

233-326-9

UNII：

I9N81SC5HD

DSSTox ID：

DTXSID40143788

HScode：

2935009090

Characteristics

PSA：

83.8

XLogP3：

4.48510

Appearance：

Yellow to yellowish green powder

Density：

1.190±0.06 g/cm3(Predicted)

Melting Point：

137-140 °C

Boiling Point：

505.5±60.0 °C(Predicted)

Flash Point：

259.5ºC

Refractive Index：

1.594

Water Solubility：

Do you have solubility information on this product that you would like to share

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)|Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

MeSH Entry Terms：

dansylcadaverine

Monodansylcadaverine Use and Manufacturing

Lysosomotropic fluorescent Probe

Computed Properties

Molecular Weight:335.5
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:335.16674822
Monoisotopic Mass:335.16674822
Topological Polar Surface Area:83.8
Heavy Atom Count:23
Complexity:447
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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