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DEPREOTIDE

DEPREOTIDE structure

DEPREOTIDE 

structure
  • CAS No:

    161982-62-3

  • Formula:

    C65H96N16O12S2

  • Chemical Name:

    DEPREOTIDE

  • Synonyms:

    Lys-Cys-Lys-(beta-DAP)-CH2CO-S-cyclo(hCys-(N-Me)Phe-Tyr-Trp-Lys-Val);lysyl-cysteinyl-lysyl-(beta-DAP) cyclo(homocysteinyl-(N-methyl)phenylalanyl-tyrosyl-tryptophyl-lysyl-valyl)thiomethyl ketone;P 829;P-829;P829 cpd;Depreotide;UNII-NDP0H8E844;NDP0H8E844;P829;Depreotide [USAN:INN]

  • Categories:

    Biochemical Engineering  >  Polypeptide

Description

Depreotide is an oligopeptide.|Depreotide is an ingredient in the EMA-withdrawn product NeoSpect.

DEPREOTIDE Basic Attributes

1357.71

1356.683472

NDP0H8E844

V09IA05

Characteristics

492

-1.03

1.24

1654.2±65.0 °C(Predicted)

954.2±34.3 °C

1.582

Drug Information

This medicinal product is for diagnostic use only.For scintigraphic imaging of suspected malignant tumours in the lung after initial detection, incombination with CT scan or chest X-ray, in patients with solitary pulmonary nodules.

Lys-Cys-Lys-(beta-DAP)-CH2CO-S-cyclo(hCys-(N-Me)Phe-Tyr-Trp-Lys-Val)

DEPREOTIDE Use and Manufacturing

Uses

Diagnostic aid (nuclear medicine imaging agent used in the detection and localization of somatostatin receptor expressing tumors).

Human drugs -> NeoSpect -> EMA Drug Category|Diagnostic radiopharmaceuticals -> Human pharmacotherapeutic group

Computed Properties

Molecular Weight:1357.7
XLogP3:0.6
Hydrogen Bond Donor Count:17
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:34
Exact Mass:1356.68350491
Monoisotopic Mass:1356.68350491
Topological Polar Surface Area:492
Heavy Atom Count:95
Complexity:2490
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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