derquantel
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derquantel
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CAS No:
187865-22-1
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Formula:
C28H37N3O4
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Chemical Name:
derquantel
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Synonyms:
derquantel;2-Deoxoparaherquamide;Unii-0L0ugk6oox;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962
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CAS No:
derquantel Use and Manufacturing
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isapotent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.
Veterinary Drug -> VETERINARY_DRUG;
Computed Properties
Molecular Weight:479.6
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Exact Mass:479.27840667
Monoisotopic Mass:479.27840667
Topological Polar Surface Area:74.3
Heavy Atom Count:35
Complexity:1010
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes