Dextromethorphan hydrochloride
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Dextromethorphan hydrochloride
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CAS No:
18609-21-7
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Formula:
C18H25NO.ClH
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Chemical Name:
Dextromethorphan hydrochloride
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Synonyms:
d-Methorphan;Delsym;Dextromethorphan;Dextromethorphan Hydrobromide;Dextromethorphan Hydrobromide, (+-)-Isomer;Dextromethorphan Hydrobromide, Monohydrate;Dextromethorphan Hydrochloride;Dextromethorphan, (+-)-Isomer;Hydrobromide, Dextromethorphan;Hydrochloride, Dextromethorphan
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CAS No:
Description
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Drug Information
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)|Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)
d-Methorphan
Computed Properties
Molecular Weight:307.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:307.1702921
Monoisotopic Mass:307.1702921
Topological Polar Surface Area:12.5
Heavy Atom Count:21
Complexity:370
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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