2,5-Dichloroquinoxaline
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2,5-Dichloroquinoxaline
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CAS No:
55687-05-3
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Formula:
C8H4Cl2N2
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Chemical Name:
2,5-Dichloroquinoxaline
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Synonyms:
Quinoxaline,2,5-dichloro-;2,5-Dichloroquinoxaline
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CAS No:
2,5-Dichloroquinoxaline Use and Manufacturing
Step 3: Analysis of the compounds gave the following results: 2, 5-dichloroquinoxaline: mp=137-138.5 C.; 1 H NMR (300 MHz, d6 -DMSO)delta7.88 (t, 1H, J=8.1 Hz, Ar-H), 8.01(d, 1H, J=8.1 Hz, Ar-H), 8.06(d, 1H, J=8.1 Hz, Ar-H), 9.08(s, 1H, Ar-H); FDMS (DMSO) m/e=198, 200, 202 (M+). Analysis of C8 H4 Cl2 N2: Theory: C, 48.28; H, 2.03; N, 14.07. Found: C, 48.24; H, 2.23; N, 13.92.Step 4: EXAMPLE 5 Preparation of N-(5-chloro-2-quinoxalinyl)benzofuran-5-sulfonamide In a manner similar to Example 4, the reaction mixture from benzofuran-5-sulfonamide (397 mg, 2.01 mmol), sodium hydride (60%, 315 mg, 7.9 mmol) and Preparation of 4-N', N'-dimethylamino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide A suspension of sodium hydride (60%, 114 mg, 2.85 mmol) in N, N-dimethylformamide (10 ml) under nitrogen at room temperature was treated with p-dimethylaminobenzenesulfonamide (214 mg, 1.07 mmol), and after stirring one hour, solid EXAMPLE 3 Preparation of N-(5-chloro-2-quinoxalinyl)-2, 3-dihydro-1-methyl-1H-indole-5-sulfonamide In a manner similar to Example 2, N-methylindoline-5-sulfonamide (212 mg, 1.0 mmol) prepared as described in Preparation 2, supra, sodium hydride (60%, 215 mg, 5.4 mmol) and
Computed Properties
Molecular Weight:199.03
XLogP3:2.7
Hydrogen Bond Acceptor Count:2
Exact Mass:197.9751535
Monoisotopic Mass:197.9751535
Topological Polar Surface Area:25.8
Heavy Atom Count:12
Complexity:165
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes