DI-8-ANEPPS
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DI-8-ANEPPS
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CAS No:
157134-53-7
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Formula:
C36H52N2O3S
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Chemical Name:
DI-8-ANEPPS
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Synonyms:
4-(2-[6-(DIOCTYLAMINO)-2-NAPHTHALENYL]ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM INNER SALT;DI-8-ANEPPS;Jpw 1153;Di-8-ANEPPS *CAS#: 157134-53-7*
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CAS No:
Drug Information
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)
1-(3-sulfonatopropyl)-4-(beta-(2-(di-n-octylamino)-6-naphthyl)vinyl)pyridinium betaine
DI-8-ANEPPS Use and Manufacturing
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Computed Properties
Molecular Weight:592.9
XLogP3:10.6
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:20
Exact Mass:592.36986470
Monoisotopic Mass:592.36986470
Topological Polar Surface Area:72.7
Heavy Atom Count:42
Complexity:789
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes