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Home > Encyclopedia > 4′,5-Dihydroxydiclofenac

4′,5-Dihydroxydiclofenac

4′,5-Dihydroxydiclofenac structure

4′,5-Dihydroxydiclofenac 

structure
  • CAS No:

    69002-86-4

  • Formula:

    C14H11Cl2NO4

  • Chemical Name:

    4′,5-Dihydroxydiclofenac

  • Synonyms:

    Benzeneacetic acid,2-[(2,6-dichloro-4-hydroxyphenyl)amino]-5-hydroxy-;2-[(2,6-Dichloro-4-hydroxyphenyl)amino]-5-hydroxybenzeneacetic acid;4′,5-Dihydroxydiclofenac

Description

ChEBI: An monocarboxylic acid that is the 4',5-dihydroxylated metabolite of diclofenac.


4',5-dihydroxydiclofenac is a monocarboxylic acid that is the 4',5-dihydroxylated metabolite of diclofenac. It has a role as a drug metabolite and a drug allergen. It is a dichlorobenzene, a monocarboxylic acid, a secondary amino compound and a member of phenols. It derives from a diclofenac.

4′,5-Dihydroxydiclofenac Basic Attributes

328.145

328.15

6US4Q8M8J7

DTXSID70219061

Characteristics

89.8

3.6

217-219 °C

Safety Information

P264, P270, P301+P312, P330, P501

H302

Drug Information

4',5-Dihydroxydiclofenac has known human metabolites that include (2S,3S,4S,5R)-6-[4-[2-(carboxymethyl)-4-hydroxyanilino]-3,5-dichlorophenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid and 2-[2-(2,6-dichloro-4-sulfooxyanilino)-5-hydroxyphenyl]acetic acid.

Computed Properties

Molecular Weight:328.1
XLogP3:3.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:327.0065132
Monoisotopic Mass:327.0065132
Topological Polar Surface Area:89.8
Heavy Atom Count:21
Complexity:359
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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