Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate

At room temperature, BrTo magnetically stirred 33 wt percent hydrogen bromide (10.00 ml, 55.2 mmol) in acetic acid was added methyl 2-(((benzyloxy)carbonyl)amino)-2-(furan-2-yl)acetate (2.89 g, 10 mmol). After stirring at room temperature for 1 hr, 150 mL of anhydrous ether was added to give 2.34 g of a grey solid. To a magnetically stirred solution of this grey solid and sodium acetate (3.53 g, 43.0 mmol) in 100 mL of water at 0° C. was added dropwise of a solution of bromine (2.215 ml, 43.0 mmol) in 20 mL of MeOH. over 30 min. After stirring at room temperature, the reaction mixture was filtered through a fritted glass funnel. The off-white solid was dissolved in 75 mL of CH

Molecular Weight:310.93
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:310.86157
Monoisotopic Mass:308.86362
Topological Polar Surface Area:59.4
Heavy Atom Count:13
Complexity:202
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes