4,5-dibromophthalic acid

4, 5-o-o-xylene6.5 g (0.025 mol)Adding 200ml of water, stirring to form a suspension, Heated to boiling.15.8 g (0.1 mol) of potassium permanganate powder was divided equally into three equal portions, The reaction mixture was added to the reaction mixture once every two hours, Co-reaction for 6 hours. The reaction mixture was cooled to room temperature, The slow addition of sodium bisulfite reduction of the remaining potassium permanganate, Until the magenta completely disappear.Potassium hydroxide was added to the reaction mixture to adjust the pH to above 12.The reaction mixture was filtered through a Buchner funnel, A clear colorless filtrate was obtained, The filtrate was a solution of potassium 4, 5-dibromophthalate.The residue was washed twice with 1percent KOH solution, The washings were combined into the filtrate.To the filtrate slowly dropping concentrated hydrochloric acid (18M) acidification to pH is about equal to 2, the precipitation of a large number of white flocculent4, 5-dibromophthalic acid.With a Buchner funnel filter, The filter cake was washed with a small amount of 1percent hydrochloric acid solution, And then placed in a desiccator silica gel drying.Obtained as a shiny white solid 7.3 g, 90percent.

Molecular Weight:323.92
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:323.84558
Monoisotopic Mass:321.84763
Topological Polar Surface Area:74.6
Heavy Atom Count:14
Complexity:230
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes