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Dicirenone

Dicirenone structure

Dicirenone 

structure
  • CAS No:

    41020-79-5

  • Formula:

    C26H36O5

  • Chemical Name:

    Dicirenone

  • Synonyms:

    Pregn-4-ene-7,21-dicarboxylic acid,17-hydroxy-3-oxo-,γ-lactone,1-methylethyl ester,(7α,17α)-;SC 26304;Dicirenone;52108-88-0

  • Categories:

    Organic Chemistry  >  Lactones

Description

SC26304 inhibits the effects of Aldosterone on urinary K+:Na+ ratios and the binding of [3H]Aldosterone to renal cytoplasmic and nuclear receptors.


Dicirenone is a steroid lactone.

Dicirenone Basic Attributes

428.565

428.56

M8K306YKSX

Characteristics

69.7

4.77180

1.187g/cm3

579.346ºC at 760 mmHg

248.372ºC

1.554

Drug Information

SC 26304

Dicirenone Use and Manufacturing

Hypotensive; aldosterone antagonist.

Computed Properties

Molecular Weight:428.6
XLogP3:2.8
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:428.25627424
Monoisotopic Mass:428.25627424
Topological Polar Surface Area:69.7
Heavy Atom Count:31
Complexity:858
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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