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Home > Encyclopedia > 16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate

16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate

16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate structure

16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate 

structure
  • CAS No:

    34990-88-0

  • Chemical Name:

    16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate

  • Synonyms:

    16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate;16,17-Epoxyestra-1,3,5(10)-triene-3,17-diol-3,17-diacetate

16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate Use and Manufacturing

Methods of Manufacturing

It can be acylated with 1, 3, 5 (10) estrien-3-ol-17 ketone (ie, estrone) with isopropenyl acetate in the presence of p-toluenesulfonic acid to produce 1, 3, 5 (10), 16-Estratetraene-3, 17-diol diacetate, then epoxidized with peracetic acid in ethylene dichloride to prepare the product.

Uses

Intermediate of estriol.

Guide of 16,17-Epoxy-3,17-dihydroxyestra-1,3,5(10)-triene-3,17-diacetate

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