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EB-47

EB-47 structure

EB-47 

structure
  • CAS No:

    366454-36-6

  • Formula:

    C24H27N9O6

  • Chemical Name:

    EB-47

  • Synonyms:

    EB-47;4-[1-(6-AMino-9H-purin-9-yl)-1-deoxy-β-D-ribofuranuronoyl]-N-(2,3-dihydro-1-oxo-1H-isoindol-4-yl)-1-piperazineacetaMide Dihydrochloride;5'-Deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)aMino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine Dihydrochloride;EB 47 DIHYDROCHLORIDE;PARP Inhibitor IX, EB-47

EB-47 Basic Attributes

537.53

537.208

Characteristics

201

-2.2

solid

H2O: 10 mg/mL, soluble

−20°C

Safety Information

3

EB-47 Use and Manufacturing

EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.

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