enopeptin A
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enopeptin A
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CAS No:
139601-96-0
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Formula:
C47H57N7O11
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Chemical Name:
enopeptin A
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Synonyms:
enopeptin A;CHEMBL4549588;NSC657143;BDBM50535811;ZINC255251360;J-007296;(2E,4E,6E,8E,10E)-N"-[(1S)-1-benzyl-2-oxo-2-[[tetramethyl(pentaoxo)[?]yl]amino]ethyl]-N-(2-hydroxy-5-oxo-cyclopenten-1-yl)dodeca-2,4,6,8,10-pentaenediamide;(2E,4E,6E,8E,10E)-N-(2-Hydroxy-5-oxocyclopenten-1-yl)-N"-[(2S)-1-oxo-3-phenyl-1-[[(3S,7S,9R,13S,16S,19S)-9,13,16,17-tetramethyl-2,6,12,15,18-pentaoxo-5-oxa-1,11,14,17-tetrazatricyclo[17.3.0.07,11]docosan-3-yl]amino]propan-2-yl]dodeca-2,4,6,8,10-pentaenediamide;(4R)-N-[(2E,4E,6E,8E,10E)-12-[(2-Hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,12-dioxo-2,4,6,8,10-dodecapentaen-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-L-proline, (6 inverted exclamation marku2)-lactone
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CAS No:
enopeptin A Use and Manufacturing
Enopeptin A is an unusual depsipeptide featuring a pentaenone side chain, reported as an antiviral by researchers at RIKEN in 1991. Enopeptin A has potent antibacterial activity against Gram positive and Gram negative bacteria, including MRSA. Enopeptin A is the most non-polar of the acyldepsipeptide (ADEP) antibiotics which include the recently rediscovered compounds, A54556 A and B, that act by activating and disregulating Clp-family proteins.
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