Enfenamic acid
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Enfenamic acid
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CAS No:
23049-93-6
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Formula:
C15H15NO2
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Chemical Name:
Enfenamic acid
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Synonyms:
Benzoic acid,2-[(2-phenylethyl)amino]-;Anthranilic acid,N-phenethyl-;2-[(2-Phenylethyl)amino]benzoic acid;RH 8;Tromaril;Enfenamic acid;N-Phenethylanthranilic acid
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CAS No:
Characteristics
49.3
3.11240
1.214g/cm3
116-117 °C
452℃
227℃
1.643
LD50 in mice (mg/kg): 575 i.p., >2000 orally (Sisoda)
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)|Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
enfenamic acid
Computed Properties
Molecular Weight:241.28
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:241.110278721
Monoisotopic Mass:241.110278721
Topological Polar Surface Area:49.3
Heavy Atom Count:18
Complexity:261
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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