Ethyl N-cyano-N-methylcarbamate

The preparation method is to add cyanamide solution to the reaction kettle, and then dropwise add ethyl chloroformate to keep the reaction temperature at about 40℃. When the pH=6～7, it is the end point. Stop the dripping and continue to stir at 40℃ for 1h After the filtrate is collected, it is transferred to another reactor. Under stirring, dimethyl sulfate is added dropwise, and the pH is adjusted to about 7 with lye. After the addition of dimethyl sulfate, the reaction is kept at 40°C for 3 hours, and filtered, The filtrate is extracted with chloroform, and the finished product is obtained after chloroform extraction and desolvation.

N-cyano-N-methyl carbamate is an intermediate of the herbicide cycloazinone.

Molecular Weight:128.13
XLogP3:0.5
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:128.058577502
Monoisotopic Mass:128.058577502
Topological Polar Surface Area:53.3
Heavy Atom Count:9
Complexity:146
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes