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tert-Butyl N-hydroxycarbamate

tert-Butyl N-hydroxycarbamate structure

tert-Butyl N-hydroxycarbamate 

structure
  • CAS No:

    36016-38-3

  • Formula:

    C5H11NO3

  • Chemical Name:

    tert-Butyl N-hydroxycarbamate

  • Synonyms:

    Carbamic acid,N-hydroxy-,1,1-dimethylethyl ester;Carbamic acid,hydroxy-,1,1-dimethylethyl ester;Carbamic acid,hydroxy-,tert-butyl ester;tert-Butoxycarbonylhydroxylamine;N-(tert-Butoxycarbonyl)hydroxylamine;tert-Butyl N-hydroxycarbamate;tert-Butyl hydroxycarbamate;N-(tert-Butyloxycarbonyl)hydroxylamine;1,1-Dimethylethyl N-hydroxycarbamate;N-t-Butyloxycarbonyl hydroxylamine;Hydroxycarbamic acid 1,1-dimethylethyl ester;NSC 131086;NSC 144620;N-Hydroxycarbamic acid tert-butyl ester;N-Boc-hydroxylamine;tert-Butoxyhydroxamic acid;N-Boc-hydroxyamine

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

White to light pink crystalline powder

tert-Butyl N-hydroxycarbamate Basic Attributes

133.15

133.15

1756546

252-836-2

GJV9GPX5T3

144620|131086

DTXSID60189587

29280090

Characteristics

58.6

0.4

White to light pink Crystalline Powder

1.1±0.1 g/cm3

58-59 °C @ Solvent: Ligroine

245.66°C (rough estimate)

105.2±18.7 °C

1.443

Slightly soluble in water.

2-8°C

Safety Information

NONH for all modes of transport

3

22-24/25

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

tert-Butyl N-hydroxycarbamate Use and Manufacturing

Used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts.

Computed Properties

Molecular Weight:133.15
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:133.07389321
Monoisotopic Mass:133.07389321
Topological Polar Surface Area:58.6
Heavy Atom Count:9
Complexity:105
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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