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Home > Encyclopedia > Diallyldimethylammonium chloride

Diallyldimethylammonium chloride

Diallyldimethylammonium chloride structure

Diallyldimethylammonium chloride 

structure
  • CAS No:

    7398-69-8

  • Formula:

    C8H16N.Cl

  • Chemical Name:

    Diallyldimethylammonium chloride

  • Synonyms:

    2-Propen-1-aminium,N,N-dimethyl-N-2-propen-1-yl-,chloride (1:1);Ammonium,diallyldimethyl-,chloride;2-Propen-1-aminium,N,N-dimethyl-N-2-propenyl-,chloride;Diallyldimethylammonium chloride;Dimethyldiallylammonium chloride;N,N-Diallyl-N,N-dimethylammonium chloride;C 1615;Nalco 7544;DADMAC;C 1615M-BR 30;M-DADMAC;Nalco TX 13645;LYFM 205-65;Newfrontier C 1615;Hercules D 1259;D 1259;AG Fix M 80;FC 704;Flocryl 4007Q;26189-16-2;54398-19-5;58829-43-9;76484-84-9;88353-41-7;104814-50-8;118338-80-0;135976-69-1;144306-62-7;147025-96-5;149611-39-2;175716-65-1;192799-01-2;2379671-23-3

  • Categories:

    Organic Chemistry  >  Amides

Description

Liquid

Diallyldimethylammonium chloride Basic Attributes

161.67200

161.09700

230-993-8

8MC08B895B

59284

DTXSID4027650|DTXSID8035714

Solid

29239000

Characteristics

0

-1.56120

Liquid

(25ºC)=1.04

164-167 °C

100ºC

n20/D 1.460

Miscible /Estimated/

Store in contact with air. Do not exceed storage temperature of 30 deg C. Protect from light.

>200 °C.

Safety Information

NONH for all modes of transport

1

R36/37/38

26-36

UC6660000

Xi

P273, P501

H412

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

The U.S. high production volume (HPV) chemicals are those which are manufactured in or imported into the United States in amounts equal to or greater than one million pounds per year. Robust Summaries include health effects, ecotoxicity data, and environmental fate information for selected chemicals. EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Available from: http://www.epa.gov/chemrtk/viewsrch.htm on Diallyldimethylammonium Chloride as of November 10, 2004.

H412 (99.1%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]|P273, and P501|Aggregated GHS information provided by 607 companies from 6 notifications to the ECHA C&L Inventory.| |Warning|H400 (13.11%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|Aggregated GHS information provided by 947 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.|H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

This product does not burn in aqueous solution. No special precautions are required. In case of fire, wear a self contained breathing apparatus. Keep containers cool during fire with water spray.

In case of accidental release, do not allow product to enter drains. Do not contaminate water. Dam up spills. Soak with inert absorbent material. If liquid has been spilled in large quantities, clean up promptly by scoop or vacuum. Keep in suitable and closed containers for disposal. After cleaning, flush area with water.

Avoid all contact with the product by ingestion, inhalation or contact with the skin, eyes and clothing. Do not breath vapors or spray mist. Wash hands and face before breaks and immediately after handling the product. When using, do not smoke. Handle in accordance with good industrial hygiene and safety practice.

Toxicity

LD50 Rat (Wistar) oral 3930 mg/kg|LD50 Rat (Sprague-Dawley) oral 2520 mg/kg

/AQUATIC SPECIES/ Groups of 10 or 20 fresh water Blue Gill Sunfish (Lepomis macrochirus) were exposed in a reconstituted medium at 64-69 °F for 96 hours. The pH was carefully monitored throughout the study. Concentrations of 0.0 (20 fish), 1.0 (10 fish), 10 (10 fish), 18 (10 fish), 24 (20 fish), 32 (20 fish), and 56.0 mg/L (10 fish) of test substance were used. Fish mortality was measured after 24, 48 and 96 hours. The only toxic sign observed was at 56 mg/L of diallyldimethylammonium chloride; some of the fish appeared slightly less active than the other fish in the study.

Drug Information

Male albino rats were placed in metabolism cages. Following intubation with 14-C diallyldimethylammonium chloride (DADMAC), one animal per time point, urine and feces were collected at 24, 48 and 72 hours. Animals were treated with 656 mg/kg (24 hours); 1585 mg/kg (48 hours) or 1591 mg/kg (72 hours) of 14-C DADMAC (100 microcuries/mL: 100 microcuries/0.9 grams. purity unspecified). Carcasses were frozen and radioactivity determined later in blood, spleen, liver, kidneys, bone marrow, and three sections of gastrointestinal tract. Carcasses, after removal of skin and feet were homogenized and radioactivity determined. While this study has marked deficiencies, it demonstrates that DADMAC is poorly absorbed. No change in clinical signs was observed in the treated animals. There was a slight weight loss in the study. The primary route of excretion for 14-C derived from DADMAC monomer was feces. ...The tissue levels for monomer were very low at each time point and there was no accumulation in any organ. The highest concentration of any organ was liver at 24 hours which had 0.0034% of the administered radioactivity. DADMAC was poorly absorbed. Of the tissues studied, the liver was found to have the largest percent uptake. The principal route of excretion was via the feces followed by the urinary pathway with a very low amount being excreted via the expired air. The largest elimination was observed to occur during the first 24 hours.

If product is inhaled, move to fresh air. In case of skin contact, rinse and wash contaminated clothing before re-use. Wash contaminated area immediately for at least 15 minutes. In case of persistent skin irritation, consult a physician. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. Keep eye wide open while rinsing and lift upper and lower lids to ensure complete removal of chemical. In case of persistent eye irritation, consult a physician. If swallowed, do not induce vomiting. Rinse mouth (never give anything by mouth to an unconscious person). Call a physician immediately.|Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

DADMAC compound

Diallyldimethylammonium chloride Use and Manufacturing

Methods of Manufacturing

... Obtained from the reaction between dimethylallylamine and allyl chloride.

Uses

DADMAC, as a cationic monomer, forms a polymer by homopolymerization or copolymerization. Its polymer can be used as an excellent formaldehyde-free fixing agent in textile dyeing and finishing aids to form a film on fabrics to improve dyeing fastness; it can be used as a retention aid and filter aid in papermaking aids, antistatic coating paper ; It can be used for decolorization, flocculation and purification in water treatment, highly efficient and non-toxic; in daily chemicals, it can be used as a shampoo, combing agent, wetting agent and antistatic agent; in oil field chemicals, it can be used Used in flocculants, water blocking agents, etc. Its main functions are electrical neutralization, adsorption, flocculation, purification, and decolorization, especially as a modifier of synthetic resin, which imparts conductivity and antistatic properties.


Intermediates

Production

100,000,000 - 250,000,000 lb|2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).

2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1), homopolymer: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).|All other basic organic chemical manufacturing|2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1): ACTIVE

Cosmetics -> Antistatic; Film forming

Computed Properties

Molecular Weight:161.67
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:161.0971272
Monoisotopic Mass:161.0971272
Heavy Atom Count:10
Complexity:91.1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Material

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