Dodecanedioic acid
-
Dodecanedioic acid
structure -
-
CAS No:
693-23-2
-
Formula:
C12H22O4
-
Chemical Name:
Dodecanedioic acid
-
Synonyms:
Dodecanedioic acid;1,10-Decanedicarboxylic acid;1,12-Dodecanedioic acid;Decamethylenedicarboxylic acid;1,10-Dicarboxydecane;n-Dodecanedioic acid;SL-AH;Corfree M 2;n-Dodecane-α,ω-dioic acid;NSC 400242;LCA 141;142610-44-4;91485-80-2
- Categories:
-
CAS No:
Description
Dodecanedioic acid (C12) is a dicarboxylic acid which is a water-soluble substance with a metabolic pathway intermediate to those of lipids and carbohydrates.
PelletsLargeCrystals|Solid
Dodecanedioic acid is an alpha,omega-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is an alpha,omega-dicarboxylic acid and a lipid. It is a conjugate acid of a dodecanedioate(2-). It derives from a hydride of a dodecane.
Dodecanedioic acid Basic Attributes
230.30100
230.30
211-746-3
978YU42Q6I
400242
DTXSID3027297
2917190090
Characteristics
74.60000
3.2
1.15
130-132 °C
205-210 °C @ Press: 1 Torr
220ºC
1.475
< 0.1 g/L (20 ºC)
-20ºC
21 mm Hg ( 222 °C)
Safety Information
NONH for all modes of transport
R36/37/38
S24/25
Xi
Stable. Incompatible with strong oxidizing agents, reducing agents. Combustible.
P305 + P351 + P338
H319
|Warning|H315 (11.14%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 476 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Toxicity
AT 1.0 MMOL, DICARBOXYLIC ACIDS DECR THE NEUROMUSCULAR INHIBITION PRODUCED BY 10-6 MOL D-TUBOCURARINE IN ISOLATED PHRENIC NERVE HEMIDIAPHRAGM PREPN FROM RATS.|THE BETA-OXIDATION RATE OF DODECANEDIOIC ACID IN RAT LIVER HOMOGENATES WAS DETERMINED BY SIMULTANEOUS MEASUREMENTS OF THE C6-C12 DICARBOXYLIC ACID IN RELATION TO TIME IN ASSAYS INCUBATED WITH DODECANEDIOIC ACID. THE BETA-OXIDN RATE OF C8-C12-DICARBOXYLIC ACIDS WAS INCREASED MANY TIMES IN HOMOGENATES FROM CLOFIBRATE-TREATED RATS. 2.0 MMOL CYANIDE WAS UNABLE TO INHIBIT THE BETA-OXIDN RATE BUT CAUSED MINOR INCREASE IN THE RATE OF BETA-OXIDN IN HOMOGENATES FROM BOTH NORMAL & CLOFIBRATE-TREATED RATS. RESULTS STRONGLY INDICATE THE EXISTENCE OF A PEROXISOMAL BETA-OXIDN OF DICARBOXYLIC ACIDS.
Drug Information
DODECANEDIOIC ACID WAS ADDED TO DISPERSED CULTURES. HUMAN EPIDERMAL CELLS & MELANOCYTES WERE EXAMINED BY ELECTRON MICROSCOPY AFTER 7, 10, 15, & 30 DAYS. APART FROM A STIMULATION OF MELANOGENESIS, DICARBOXYLIC ACIDS CAUSED NO DETECTABLE DAMAGE TO MELANOCYTES, NOR DID THEY PREVENT GROWTH OF A 2ND GENERATION OF CELLS.
1,10-decanedicarboxylic acid
Dodecanedioic acid Use and Manufacturing
Induced mutation of dodecanedioic acid producing Candida tropicalis.
Adhesives and sealant chemicals
10,000,000 - 50,000,000 lb
All other chemical product and preparation manufacturing|Dodecanedioic acid: ACTIVE|DIBASIC ACID ESTERS ARE BETTER COSMETIC MATERIALS THAN CONVENTIONALLY USED LANOLIN OR PETROLATUM IN TERMS OF ODOR, COLOR, STABILITY, AND HOMOGENEITY.
Fatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Dicarboxylic acids [FA0117]
Computed Properties
Molecular Weight:230.30
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:230.15180918
Monoisotopic Mass:230.15180918
Topological Polar Surface Area:74.6
Heavy Atom Count:16
Complexity:179
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Dodecanedioic acid
-
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed AdditiveInquiryCAS No.: 693-23-2Grade: Industrial GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
9 YRS
Business licensed Certified factoryManufactory Supplier of Undecanedioic Acid,Dodecanedioic Acid,Brassylic Acid,Tetradecanedioic Acid,Pentadecanedioic Acid,Hexadecanedioic Acid -
![Turkey]()
TR
4 YRS
Business licensed Verified SupplierTrader Supplier of Chemicals -
![China]()
CN
10 YRS
Business licensed Certified factoryManufactory Supplier
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8