Pyridoxal 5′-phosphate monohydrate
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Pyridoxal 5′-phosphate monohydrate
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CAS No:
41468-25-1
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Formula:
C8H10NO6P.H2O
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Chemical Name:
Pyridoxal 5′-phosphate monohydrate
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Synonyms:
4-Pyridinecarboxaldehyde,3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-,hydrate (1:1);4-Pyridinecarboxaldehyde,3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-,monohydrate;Pyridoxal 5′-phosphate monohydrate;MC 1
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CAS No:
Description
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phos
Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.|This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
Pyridoxal 5′-phosphate monohydrate Basic Attributes
265.15700
265.03500
609-929-1
5V5IOJ8338
DTXSID7046594
C81627
2936250000
Drug Information
A group of water-soluble vitamins, some of which are COENZYMES. (See all compounds classified as Vitamin B Complex.)
Phosphate, Pyridoxal
Pyridoxal 5′-phosphate monohydrate Use and Manufacturing
The active form of vitamin b 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate.
Computed Properties
Molecular Weight:265.16
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:265.03513872
Monoisotopic Mass:265.03513872
Topological Polar Surface Area:118
Heavy Atom Count:17
Complexity:292
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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Pyridoxal 5′-phosphate monohydrate
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