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Monosodium citrate

Monosodium citrate structure

CAS No:
18996-35-5
Formula:
C6H8O7.Na
Chemical Name:
Monosodium citrate
Synonyms:
1,2,3-Propanetricarboxylic acid,2-hydroxy-,sodium salt (1:1);Citric acid,monosodium salt;1,2,3-Propanetricarboxylic acid,2-hydroxy-,monosodium salt;Sodium citrate (NaC6H7O7);Monosodium citrate;Sodium dihydrogen citrate;Monosodium dihydrogen citrate;Citrofluyl;E 331i;920537-27-5;1189691-15-3
Categories:
Cosmetic Ingredient > Buffering

Description

Monosodium citrate, also known as sodium dihydrogen citrate, is an acid salt of citric acid with the chemical formula NaH₂C₆H₅O₇. It appears as a white, crystalline powder that is highly soluble in water and practically insoluble in ethanol. The compound has a slightly acidic taste and a pH of 3.5–3.8 in a 5% aqueous solution. Monosodium citrate is less hygroscopic than citric acid, making it less prone to caking and preferred in dry formulations.

Monosodium citrate Basic Attributes

Molecular Weight：

214.10500

Exact Mass：

214.00900

HScode：

2918150000

Characteristics

PSA：

134.96000

XLogP3：

-2.58320

Appearance：

white crystalline powder

Melting Point：

212ºC(lit.)

Boiling Point：

309.6ºC at 760mmHg

Flash Point：

155.2ºC

Water Solubility：

H2O: 0.25 M at 20 °C, clear, colorless

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R36

safety instructions：

22-24/25

RTECS Number：

GE7950000

Marks：

Monosodium citrate Use and Manufacturing

Monosodium citrate, more correctly, sodium dihydrogen citrate, is an acid salt of citric acid. disodium citrate and trisodium citrate are also known. It can be prepared by partial neutralisation of an aqueous solution of sodium bicarbonate or carbonate with citric acid.It is highly soluble in water and practically insoluble in ethanol. Monosodium citrate is used as an anticoagulant in donated blood.

Material

Citric acid

Drug Function and Efficacy

This product is an H2 receptor inhibitor, which has the effect of inhibiting gastric acid secretion. It is rapidly absorbed through the gastrointestinal tract after oral administration.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Ranitidine Hydrochloride Effervescent Granules
Ingredients	Each package of this product contains 0.15g of ranitidine hydrochloride. The auxiliary materials are sodium dihydrogen citrate, sodium bicarbonate and lemon essence.
Indication	1. When used with procainamide, the clearance rate of procainamide may be reduced. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	1.5g per bag (containing 0.15g of ranitidine)
Manufacturer	Hangzhou Conba Pharmaceutical Co., Ltd.

Registered Holders

ANMOL CHEMICALS PRIVATE LTD

United States
Active
Zhejiang Cdmo Pharmaceutical Co., Ltd

China
Active

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Guide of Monosodium citrate

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Material
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
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Monosodium citrate

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