4-[(3-Pyridinylcarbonyl)amino]butanoic acid

10percent Palladium charcoal (lOmmol) and dry Methanol (10 vol) were placed in a50 mL flask, and then compound- 2 (10 mmol) was added while stirring. Flushed with nitrogen and followed by hydrogen gas. Reaction left for stirring vigorously at room temperature for 2.0 h at hydrogen atmosphere, on completion the reaction mixture was filtered over celite and washed with methanol. The organic layer was evaporated and residue was dissolved in ethyl acetate, and was washed with water. The organic layers were dried over sodium sulfate, filtered and evaporated to yield compound-3 (yield: 90percent).Synthesis of Compound-3 : [001 0} 10percent .Palladium charcoal (lOmmoi) and dry Methanol (10 vol) were placed in a 50 m.L flask, and then compotmd-2 (10 mmol) was added while stirring. Flushed with nitrogen and followed by hydrogen gas. Reaction kept stirring for vigorously at room temperature for 2.0 h at hydrogen atmosphere, on completion of the reaction mixture was filtered over eel he and washed with methanol. The organic layer was evaporated and residue was dissolved in ethyl acetate, and was washed with water. The organic layers were dried over sodium sulfate, filtered and evaporated to give yield compound-3 (yield: 90percent).M.F: CioHn iO;, ; Mol. Wt.: 208.21. |01

anti-cancer agent

Molecular Weight:208.21
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:208.08479225
Monoisotopic Mass:208.08479225
Topological Polar Surface Area:79.3
Heavy Atom Count:15
Complexity:231
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes