 Home > Encyclopedia > Sodium picosulfate

Sodium picosulfate

Sodium picosulfate structure

CAS No:
10040-45-6
Formula:
C18H15NO8S2.2Na
Chemical Name:
Sodium picosulfate
Synonyms:
Phenol,4,4′-(2-pyridinylmethylene)bis-,1,1′-bis(hydrogen sulfate),sodium salt (1:2);Phenol,4,4′-(2-pyridylmethylene)di-,bis(hydrogen sulfate) (ester) disodium salt;Phenol,4,4′-(2-pyridinylmethylene)bis-,bis(hydrogen sulfate) (ester),disodium salt;4,4′-(2-Pyridylmethylene)diphenol bis(hydrogen sulfate) disodium salt;Sodium picosulfate;Picosulfol;Disodium bis[4-[(hydroxysulfonyl)oxy]phenyl](2-pyridyl)methane;Picosulfate sodium;Evacuol;Guttalax;Laxoberal;Rapilax;DA 1773;Laxoberon;Picolax;LA 391;Pico-Salax;Guttalax-Fher;Neopax;PicoPrep;27946-28-7;144857-73-8;1990499-10-9
Categories:
Inorganic Chemistry > Inorganic Salts

Description

Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.Target: OthersSodium Picosulfate displays cytotoxic effects on cultured liver cells. 800 and 1600 mg/mL induces dose-dependently vacuolic and fatty change as well as necrosis combined with a lowered mitotic activity and a slight increase in LDH values of the rapidly growing cultured liver cells of rabbit. Comparable but less severe effects are observed in 4-day old liver cell cultures of rat,

Sodium picosulfate is an aryl sulfate and a member of pyridines.

Sodium picosulfate Basic Attributes

Molecular Weight：

48141

Exact Mass：

480.987793

EC Number：

233-120-9

UNII：

VW106606Y8

DSSTox ID：

DTXSID7048663

ATC Code：

A - Alimentary tract and metabolism

HScode：

2933399090

Characteristics

PSA：

163

XLogP3：

4.10140

Melting Point：

273 °C (decomp)

Storage Conditions：

Hygroscopic, Refrigerator, Under Inert Atmosphere

Safety Information

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents that are used to stimulate evacuation of the bowels. (See all compounds classified as Cathartics.)

MeSH Entry Terms：

4,4'-(2-picolylidene)bisphenylsulfuric acid

Sodium picosulfate Use and Manufacturing

Uses

Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Sodipic Picofast, Laxoberal, Laxoberon, Purg-Odan, Picolax, Guttalax, Namilax, Pico-Salax and Prepopik among others. PicoPrep is based on Sodium picosulphate.

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:481.4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:480.98779728
Monoisotopic Mass:480.98779728
Topological Polar Surface Area:163
Heavy Atom Count:31
Complexity:633
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Recommended Suppliers of Sodium picosulfate

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Sodium picosulfate

CAS No.: 10040-45-6

Content: 99.00%

Inquiry
Xiamen Eagle Chemical Corporation Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of Dimethyl sufoxide

Sodium picosulfate(10040-45-6)

Unit Price: $1500-1550 /MT FOB

CAS No.: 10040-45-6

Grade: Industrial Grade

Content: 99.5%

Inquiry
nordhuns Contact Supplier

CN
6 YRS

Business licensed

Distributor Supplier of 4-ISOPROPYL-3-METHYLPHENOL,4-Hydroxy-3-methoxyacetophenone,Benzarone,Sodium picosulfate

Sodium picosulfate

CAS No.: 10040-45-6

Inquiry
Xian ZB Biotech Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Herb Extracts,Cosmetic raw materails,API

High Quality Purity 99% CAS 10040-45-6 Sodium Picosulfate Powder

CAS No.: 10040-45-6

Grade: Pharmaceutical Grade

Content: 0.00%

Inquiry

Learn More Other Chemicals

Desacetyl Cephapirin SodiuM Salt

104557-24-6
D-Fructose, 1,6-bis(dihydrogen phosphate), sodium salt (1:4)

23784-19-2
Glucose 1-phosphate sodium salt

17364-14-6
Poly(oxy-1,2-ethanediyl), α-(carboxymethyl)-ω-(decyloxy)-, sodium salt (1:1) Formula

38815-93-9
DIAMMONIUM SODIUM HEXANITRORHODATE(III)& Formula

14640-47-2
DECANOIC ACID-CARBOXY-14C SODIUM Formula

94033-36-0
1H-Tetrazole-1-acetic acid, 2,5-dihydro-5-thioxo-, sodium salt (1:1) Structure

113221-74-2
Phosphonic acid, (dichloromethylene)bis-, sodium salt Structure

29329-69-9
What is Benzoic acid, 2,3-dichloro-, sodium salt (1:1)

118537-84-1
What is Sodium arsenate heptahydrate

10048-95-0

Hot Searches: copper hydroxide; formula of calcium sulphate; pentothal; ammonium sulfide formula; molecular mass of benzaldehyde; barium bromide

Guide of Sodium picosulfate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

Sodium picosulfate

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.