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Colistin sulfate

Colistin sulfate structure

CAS No:
1264-72-8
Formula:
H2O4S.xUnspecified
Chemical Name:
Colistin sulfate
Synonyms:
Colistin,sulfate (salt);Colistin sulfate;Colimycin sulfate;Colomycin syrup;Polymyxin E,sulfate (salt);Polymyxin E sulfate;Belcomycin;Colomycin;Nipoxyme;126777-31-9;8055-19-4;11039-78-4;12737-32-5;51810-43-6;55606-05-8
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Colistin is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.

Colistin sulfate Basic Attributes

Molecular Weight：

2801.27

Exact Mass：

1266.73295702 g/mol

EC Number：

215-034-3

HScode：

29419000

Characteristics

PSA：

573.64000

XLogP3：

1.96320

Appearance：

Powder

Density：

1.3±0.1 g/cm3

Melting Point：

200-220°C

Boiling Point：

1536.8ºC at 760mmHg

Flash Point：

883.5±34.3 °C

Refractive Index：

1.575

Water Solubility：

H2O: soluble 50mg/mL

Storage Conditions：

2-8°C

Vapor Pressure：

0mmHg at 25°C

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

TR1500000

Marks：

Precautionary statement(s)：

Missing Phrase - N15.00950417

Hazard Statements：

H301

Colistin sulfate Use and Manufacturing

Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistins A and B.[a]D= -65?(c= 1, Water) LOD: 3%

Price Analysis

Make your Colistin sulfate purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Colistin sulfate prices .

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Colistin Sulfate Granules
Specifications	1g: 1 million units

Colistin Sulfate Tablets
Ingredients	The main ingredient is colistin sulfate.
Indication	Sulfonamides, TMP, rifampicin and semi-synthetic penicillins can enhance the antibacterial effect of polymyxins against Escherichia coli, Enterobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa, etc.
Specifications	500,000 units

Registered Holders

XELLIA PHARMACEUTICALS ApS

Denmark
Active
LIVZON GROUP FUZHOU FUXING PHARMACEUTICAL CO., LTD.

European Union
Active
ANHUI APELOA BIOTECHNOLOGY CO., LTD.

European Union
Active

See More Registered Holders

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