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Home > Encyclopedia > p-Hydroxybenzoic acid ethyl ester sodium salt

p-Hydroxybenzoic acid ethyl ester sodium salt

pharmaceutical raw materials
p-Hydroxybenzoic acid ethyl ester sodium salt structure

p-Hydroxybenzoic acid ethyl ester sodium salt 

structure
  • CAS No:

    35285-68-8

  • Formula:

    C9H11NaO3

  • Chemical Name:

    p-Hydroxybenzoic acid ethyl ester sodium salt

  • Synonyms:

    p-Hydroxybenzoic acid ethyl ester sodium salt;SODIUM ETHYL-P-HYDROXYBENZOATE;SODIUM ETHYL 4-HYDROXYBENZOATE;sodium 4-ethoxycarbonylphenoxide;benzoicacid,4-hydroxy-,ethylester,sodiumsalt;Benzoicacid,p-hydroxy-,ethylester,sodiumderiv.;ETHYL-P-HYDROXYBENZOATE SODIUM SALT;ETHYL-4-HYDROXYBENZOIC ACID SODIUM SALT

  • Categories:

    Cosmetic Ingredient  >  Cosmetic Preservative

Description

White or almost white, hygroscopic, crystalline powder.


White, crystalline hygroscopic powder

p-Hydroxybenzoic acid ethyl ester sodium salt Basic Attributes

190.17

188.044937

252-487-6

Z0D00IVA10

DTXSID0042402

White to Off-White

2918 29 00

Characteristics

49.4

2.00710

1.34[at 20℃]

>115°C(free ester)

297°C (1013 hPa)(free ester),(decomposition)

120.3ºC

1000g/L at 23℃

LD50 orally in Rabbit: > 2000 mg/kg

Non flammable

10 (1g/l, H2O, 20°C)

8.4[at 20 ℃]

Store at +15°C to +25°C.

Safety Information

WGK 1 slightly water endangering

P280, P305+P351+P338, P310

H318

|Danger|H318 (77.19%): Causes serious eye damage [Danger Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, P310, and P337+P313|Aggregated GHS information provided by 228 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.

p-Hydroxybenzoic acid ethyl ester sodium salt Use and Manufacturing

Uses

This product is a water-soluble preservative, the main features are safe, efficient and broad-spectrum antibacterial. Widely used in the pharmaceutical industry (preparation of Chinese herbal medicines, Chinese medicines; disinfection of medical devices); food industry (dairy products, pickled products, beverages, fruit juices, jellies, cakes, etc.); antisepsis in the textile industry (textiles, cotton yarn, chemical fiber) . And other antiseptics such as cosmetics, feed, and daily-use industrial products. 20 kg cardboard drum with compound aluminum film bag inside.


Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Food additives|Cosmetics -> Preservative

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