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Propidium iodide

Propidium iodide structure

CAS No:
25535-16-4
Formula:
C27H34N4.2I
Chemical Name:
Propidium iodide
Synonyms:
Phenanthridinium,3,8-diamino-5-[3-(diethylmethylammonio)propyl]-6-phenyl-,iodide (1:2);Phenanthridinium,3,8-diamino-5-[3-(diethylmethylammonio)propyl]-6-phenyl-,diiodide;3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium iodide methiodide;Ammonium,[3-(3,8-diamino-6-phenyl-5-phenanthridinio)propyl]diethylmethyl-,diiodide;Propidium iodide;Propidium diiodide;3,8-Diamino-5-(diethylmethylaminopropyl)-6-phenylphenanthridinium diiodide
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Propidium iodide is an organic iodide salt. It contains a propidium.|Propidium Iodide is a fluorescent nucleic acid dye which binds only to double-stranded nucleic acids. It has a molecular weight of 668.4, an absorbance maximum of 535nm, and an emission maximum of 617 nm. It is commonly used to determine the DNA content of a cell or to discriminate viable from non-viable cells.|Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Propidium iodide Basic Attributes

Molecular Weight：

668.4

Exact Mass：

668.08729

EC Number：

247-081-0

UNII：

TP416O228T

NCI Thesaurus Code：

C72903

Safety Information

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P201, P202, P261, P264, P271, P280, P281, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 162 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)|Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA. (See all compounds classified as Intercalating Agents.)|Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)

MeSH Entry Terms：

Diiodide, Propidium

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CAS No.: 25535-16-4

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Propidium iodide

CAS No.: 25535-16-4

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