Benzeneethanamine, N,α-dimethyl-, hydrochloride (1:1)

185.7

185.0971272 g/mol

206-093-6

169506|169505|22367

2811

DTXSID3048865

12 Ų

133-135 °C

greater than or equal to 100 mg/mL at 68° F (NTP, 1992)

LD50 oral in rabbit: 10500ug/kg

Water soluble.

Hydrocarbons, Aromatic

An acidic salt of the amine, therefore behaves as a weak acid.

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under ambient temperatures. This compound is a Schedule II DEA Controlled Substance and is to be stored according to State and Federal Regulations. Refer to Code of Federal Regulations Title 21 Part 1300 to End. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

SYMPTOMS: Symptoms of exposure to this compound include elevation of blood pressure, tachycardia, palpitation, psychotic episodes (rare), dizziness, dysphoria, overstimulation, euphoria, insomnia, tremor, restlessness, headache, exacerbation of motor and phonic tics, Tourette's syndrome, diarrhea, constipation, dryness of the mouth, unpleasant taste, other gastrointestinal disturbances, urticaria, impotence, changes in libido and suppression of growth in children. Other symptoms include metallic taste, anorexia, difficulty in micturition, mydriasis, agitation, skin rashes and abdominal pain. Exposure can cause increased awareness, lessening of fatigue, exhilaration, sweating, flushing or pallor, dehydration, purposeless motions, bradycardia, extrasystoles, heart block, tachypnea, anxiety, paranoid and hostile behavior, and delirium. Chronic symptoms include severe dermatoses, marked insomnia, irritability, hyperactivity, personality changes and psychosis. Other chronic symptoms include aplastic anemia, pancytopenia, gynecomastia and angiitis. Exposure to large doses may cause hyperreflexia, rapid respiration, confusion, assualtiveness, hallucinations, panic states, hyperpyrexia, rhabdomyolysis, fatigue and mental depression following central nervous system stimulation, arrhythmias, hypertension or hypotension, circulatory collapse, nausea, vomiting, convulsions, coma and death. Large doses may also cause fever or chilliness, talkativeness, disorientation and aggressive behavior. Other symptoms from large doses include acts of self-destruction and mania. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of nitrogen oxides and hydrogen chloride. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Benzeneethanamine, N,.alpha.-dimethyl-, hydrochloride (1:1), (.alpha.S)-: INACTIVE

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients