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Tramazoline hydrochloride

Tramazoline hydrochloride structure

CAS No:
3715-90-0
Formula:
C13H17N3.ClH
Chemical Name:
Tramazoline hydrochloride
Synonyms:
1H-Imidazol-2-amine,4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-,hydrochloride (1:1);2-Imidazoline,2-[(5,6,7,8-tetrahydro-1-naphthyl)amino]-,monohydrochloride;1H-Imidazol-2-amine,4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-,monohydrochloride;Tramazoline hydrochloride;KB 227;Rhinaspray;Rhinospray;Ellatun;Rinogutt;Towk;Biciron;Rhinogutt

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Description

Tramazoline hydrochloride is a member of tetralins.

Tramazoline hydrochloride Basic Attributes

Molecular Weight：

251.759

Exact Mass：

251.1189253 g/mol

EC Number：

223-064-3

UNII：

4DG710Q678

Characteristics

PSA：

41 Å²

Melting Point：

172-174 °C

Toxicity：

LD50 orally in mice: 195 mg/kg (Engelhorn, Klupp)

Safety Information

GHS Classification：

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P273, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P391, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH：

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

MeSH Entry Terms：

2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline

Tramazoline hydrochloride Use and Manufacturing

Alpha-adrenoceptor agonist.

Computed Properties

Molecular Weight:251.75
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:251.1189253
Monoisotopic Mass:251.1189253
Topological Polar Surface Area:36.4
Heavy Atom Count:17
Complexity:274
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Guide of Tramazoline hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

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