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Viridicatumtoxin

Viridicatumtoxin structure

Viridicatumtoxin 

structure
  • CAS No:

    39277-41-3

  • Formula:

    C30H31NO10

  • Chemical Name:

    Viridicatumtoxin

  • Synonyms:

    Spiro[2-cyclohexene-1,2′(1′H)-cyclopenta[de]naphthacene]-9′-carboxamide,7′,7′a,8′,11′,11′a,12′-hexahydro-5′,6′,7′a,10′,11′a,12′-hexahydroxy-3′-methoxy-2,6,6-trimethyl-7′,8′-dioxo-,(1R,7′aR,11′aR,12′R)-rel-(-)-;Spiro[2-cyclohexene-1,2′(1′H)-cyclopenta[de]naphthacene]-9′-carboxamide,7′,7′a,8′,11′,11′a,12′-hexahydro-5′,6′,7′a,10′,11′a,12′-hexahydroxy-3′-methoxy-2,6,6-trimethyl-7′,8′-dioxo-,(2′α,7′aβ,11′aβ,12′β)-(-)-;rel-(-)-(1R,7′aR,11′aR,12′R)-7′,7′a,8′,11′,11′a,12′-Hexahydro-5′,6′,7′a,10′,11′a,12′-hexahydroxy-3′-methoxy-2,6,6-trimethyl-7′,8′-dioxospiro[2-cyclohexene-1,2′(1′H)-cyclopenta[de]naphthacene]-9′-carboxamide;Viridicatumtoxin;NSC 159628

Viridicatumtoxin Basic Attributes

565.57

565.57

Characteristics

207.84000

2.48220

1.3203

235°C (rough estimate)

630.75°C (rough estimate)

384.3ºC

1.6310 (estimate)

Viridicatumtoxin Use and Manufacturing

Viridicatumtoxin is a tetracycline-like metabolite produced by several species of Penicillium, first isolated in 1976 as a mycotoxin. Initial testing revealed that viridicatumtoxin caused myocardial deterioration, renal tubule necrosis and spleen atrophy. Analogous to the related tetracyclines, viridicatumtoxin was found to be a potent antibacterial, with activity against S. aureus including MRSA and QRSA strains. Little has been published on the mode of action of viridicatumtoxin.

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