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Ramoplanin

Ramoplanin structure

CAS No:
76168-82-6
Chemical Name:
Ramoplanin
Synonyms:
Ramoplanin;Antibiotic A 16686;MDL 62198;A 16686;A 16686A
Categories:
Biochemical Engineering > Polypeptide

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Ramoplanin Basic Attributes

Molecular Weight：

2254.0597

Exact Mass：

2253.2144556

Characteristics

PSA：

852.29000

XLogP3：

3.50660

Melting Point：

210-230°

Toxicity：

LD50 in mice (mg/kg): 328 i.p., 122 i.v.; orally in rats: 2000 mg/kg (Pallanza)

Safety Information

wgk germany：

nwg

hazard class code：

safety instructions：

26-39

RTECS Number：

VE5050000

Marks：

GHS Classification：

|Danger|H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]|P280, P305+P351+P338, and P310|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

MeSH Entry Terms：

A 16686

Ramoplanin Use and Manufacturing

Ramoplanin is a complex of three high molecular weight glycolipodepsipeptides, varying in the chain length and shape of the dieneone lipid side-chain. Ramoplanin was isolated in the early 1980s as the major metabolite of a strain of Actinoplanes with antiviral and antibiotic activity against drug resistant Gram positive isolates. Ramoplanin acts by inhibiting cell wall biosynthesis via a different mechanism from the vancomycin-related glycopeptides.

Computed Properties

Molecular Weight:2254.1
XLogP3:-4.8
Hydrogen Bond Donor Count:31
Hydrogen Bond Acceptor Count:32
Rotatable Bond Count:61
Exact Mass:2253.2144556
Monoisotopic Mass:2252.2111008
Topological Polar Surface Area:852
Heavy Atom Count:158
Complexity:4810
Defined Atom Stereocenter Count:15
Undefined Atom Stereocenter Count:7
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Ramoplanin

CAS No.: 76168-82-6

Content: 99.00%

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Ramoplanin 98% white powder cas 76168-82-6/ Youngshe

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CAS No.: 76168-82-6

Grade: Chemical Grade

Content: 98%

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Guide of Ramoplanin

Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
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