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(R)-(+)-Tetrahydro-2-furoic acid

(R)-(+)-Tetrahydro-2-furoic acid structure

(R)-(+)-Tetrahydro-2-furoic acid 

structure
  • CAS No:

    87392-05-0

  • Formula:

    C5H8O3

  • Chemical Name:

    (R)-(+)-Tetrahydro-2-furoic acid

  • Synonyms:

    (R)-(+)-2-Tetrahydrofuroic acid, 99% (98% ee) 1GR;(R)-(+)-Tetrahydro-2-furoic acid, 99% (98% ee);(R)-(+)-Tetrahydro-2-furoic acid 99%;(R)-(+)-Tetrahydrofuran-2-carboxylic Acid;(R)-(+)-Tetrahydro-2-furoic acid≥ 99% (GC, Chiral purity);(R)-Tetrahydrofuran-2-carboxylic Acid,99%e.e.;(R)-2-TETRAHYDROFUROIC ACID;(R)-2-CARBOXY-TETRAHYDROFUROIC-ACID

  • Categories:

    Active Pharmaceutical Ingredients  >  Other Chemical Drugs

Description

(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.


Colorless to light yellow liquid

(R)-(+)-Tetrahydro-2-furoic acid Basic Attributes

116.12

116.047344113

4658739

627-523-2

7396HFQ44J

Colorless to Light yellow

29321900

Characteristics

1.209 g/mL at 25 °C(lit.)

128-129 °C13 mm Hg(lit.)

n20/D1.46(lit.)

3.60±0.20(Predicted)

Keep in dark place,Sealed in dry,Room Temperature

Safety Information

III

8

UN 3265 8/PG 3

3

C,Xi

26-36/37/39-45-36

C,Xi

22-34-36/37/38

UN 3265 8/PG 3

|Danger|H302 (86.96%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, and P501|Aggregated GHS information provided by 46 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

(R)-(+)-Tetrahydro-2-furoic acid Use and Manufacturing

(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

Computed Properties

Molecular Weight:116.11
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:116.047344113
Monoisotopic Mass:116.047344113
Topological Polar Surface Area:46.5
Heavy Atom Count:8
Complexity:99.8
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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