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STATIL

STATIL structure

STATIL 

structure
  • CAS No:

    72702-95-5

  • Formula:

    C17H12BrFN2O3

  • Chemical Name:

    STATIL

  • Synonyms:

    STATIL;[3-(4-BROMO-2-FLUOROBENZYL)-4-OXO-3H-PHTHALAZIN-1-YL]ACETIC ACID;Ponalrestat;3-(4-BROMO-2-FLUOROBENZYL)-4-OXO-3H-PHTHALAZIN-1-YL]ACETIC ACID (STATIL);3-[(4-Bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid;ICI-128436;ICI-plc;MK-538

Description

2-[3-[(4-bromo-2-fluorophenyl)methyl]-4-oxo-1-phthalazinyl]acetic acid is a member of phthalazines.

STATIL Basic Attributes

391.19

390.00153 g/mol

2CV0A5G64E

DTXSID1045665

2933990090

Characteristics

72.19000

2.97350

1.60

184-186℃ (DEC.)

576.3ºC

302.4ºC

1.663

Store at RT

Safety Information

36/37/38

26-36/37/39

Drug Information

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Substances which lower blood glucose levels. (See all compounds classified as Hypoglycemic Agents.)

3-(4-bromo-2-fluorobenzyl)-3,4-dihydro-4-oxo-3H-phthalazin-1-ylacetic acid

STATIL Use and Manufacturing

Inhibitor (aldose reductase).

Computed Properties

Molecular Weight:391.2
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:390.00153
Monoisotopic Mass:390.00153
Topological Polar Surface Area:70
Heavy Atom Count:24
Complexity:542
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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