 Home > Encyclopedia > Etoposide phosphate

Etoposide phosphate

Etoposide phosphate structure

CAS No:
117091-64-2
Formula:
C29H33O16P
Chemical Name:
Etoposide phosphate
Synonyms:
Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-,(5R,5aR,8aR,9S)-;Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-,[5R-[5α,5aβ,8aα,9β(R*)]]-;Pyrano[3,2-d]-1,3-dioxin,furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one deriv.;(5R,5aR,8aR,9S)-5-[3,5-Dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one;BMY 40481;Etoposide phosphate;Etoposide 4′-phosphate;Etopofos;Etopophos;122332-48-3;138067-47-7;149027-99-6
Categories:
Organic Chemistry > Phosphines

Request for Quotation

Etoposide phosphate Basic Attributes

Molecular Weight：

668.54

Exact Mass：

668.54

EC Number：

630-364-1

DSSTox ID：

DTXSID9048645

Characteristics

PSA：

207 Å²

Density：

1?+-.0.1 g/cm3

Boiling Point：

907.7±75.0 °C(Predicted)

PKA：

1.13±0.50

Drug Information

Drug Indication：

Drug: Etoposidephosphate

MeSH：

Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)

MeSH Entry Terms：

BMY 40481-30

Etoposide phosphate Use and Manufacturing

As a bioequivalent prodrug of the DNA topoisomerase II inhibitor Etoposide (E933750), Etoposide phosphate can be used in the treatment of a wide variety of hematological malignancies and solid tumors.

Computed Properties

Molecular Weight:668.5
XLogP3:-0.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:7
Exact Mass:668.15062196
Monoisotopic Mass:668.15062196
Topological Polar Surface Area:207
Heavy Atom Count:46
Complexity:1140
Defined Atom Stereocenter Count:4
Undefined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

No specific description of pharmacological action is clear from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Etoposide Phosphate for Injection
Specifications	0.1g (based on C29H32013)
Manufacturer	Chongqing Huapont Pharmaceutical Co., Ltd.

Etoposide phosphate
Manufacturer	Chongqing Shengkai Pharmaceutical Co., Ltd.

Etoposide Phosphate for Injection
Specifications	100mg (as etoposide)
Manufacturer	Hainan Tongyong Kangli Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

NIPPON KAYAKU CO.LTD.

Brazil
Active
Chongqing Shengkai Pharmaceutical Co., Ltd.

China
Active
Hainan Huluwa Pharmaceutical Group Co., Ltd.

China
Active