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Home > Encyclopedia > N-Pyrazinylcarbonyl-L-phenylalanineMethylEster

N-Pyrazinylcarbonyl-L-phenylalanineMethylEster

N-Pyrazinylcarbonyl-L-phenylalanineMethylEster structure

N-Pyrazinylcarbonyl-L-phenylalanineMethylEster 

structure
  • CAS No:

    73058-37-4

  • Formula:

    C15H15N3O3

  • Chemical Name:

    N-Pyrazinylcarbonyl-L-phenylalanineMethylEster

  • Synonyms:

    methyl 3-phenyl-2-(pyrazine-2-carbonylamino)propanoate;Bortezomib Acid Methyl Ester;Bortezomib Impurity R;(S)-methyl 3-phenyl-2-(pyrazine-2-carboxamido)propanoate;Bortezomib Imp.F;N-PYRAZINYLCARBONYLPHENYLALANINE METHYL ESTER;3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester;N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester

N-Pyrazinylcarbonyl-L-phenylalanineMethylEster Basic Attributes

285.3

285.11134135

DTXSID90503277

Characteristics

81.18000

1.38160

1.238±0.06 g/cm3

55 °C

533.2±50.0 °C(Predicted)

11.75±0.46

N-Pyrazinylcarbonyl-L-phenylalanineMethylEster Use and Manufacturing

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester can be used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

Computed Properties

Molecular Weight:285.30
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:285.11134135
Monoisotopic Mass:285.11134135
Topological Polar Surface Area:81.2
Heavy Atom Count:21
Complexity:356
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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