CLASTO-LACTACYSTINBETA-LACTONE
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CLASTO-LACTACYSTINBETA-LACTONE
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CAS No:
154226-60-5
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Formula:
C10H15NO4
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Chemical Name:
CLASTO-LACTACYSTINBETA-LACTONE
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Synonyms:
OMURALIDE;LACTACYSTIN, CLASTO-, BETA-LACTONE;BETA-CLASTOLACTACYSTIN;CLASTO-LACTACYSTIN BETA-LACTONE;1R-[1S-1HYDROXY-2-METHYLPROPYL]-4R-METHYL-6-OXA-2-AZABICYCLO[3.2.0]HEPTANE-3,7-DIONE;clasto-lactacystin β-lactone;Clasto-lactacystin (OMuralide);(1R,4R,5S)-1-[(1S)-1-Hydroxy-2-Methylpropyl]-4-Methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione
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CAS No:
CLASTO-LACTACYSTINBETA-LACTONE Use and Manufacturing
A cell permeable, irreversible proteasome inhibitor. It is 20-fold more potent than Lactacystin. Lactacytstin spontaneously converts to clasto-lactacystin in biological systems. Clasto-lactacystin is the only cell permeable form of lactacystin. Induces neurite growth and inhibits cell cycle progression similar to lactacytin.
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