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Fendiline

Fendiline structure

CAS No:
13042-18-7
Formula:
C23H25N
Chemical Name:
Fendiline
Synonyms:
Benzenepropanamine,γ-phenyl-N-(1-phenylethyl)-;Benzylamine,N-(3,3-diphenylpropyl)-α-methyl-;γ-Phenyl-N-(1-phenylethyl)benzenepropanamine;N-(1-Phenylethyl)-3,3-diphenylpropylamine;Fendiline;Fendilin;N-(3,3-Diphenylpropyl)-α-methylbenzylamine;Phendilin;dl-Fendiline;(±)-Fendiline;3,3-Diphenyl-N-(1-phenylethyl)propan-1-amine;84367-09-9
Categories:
Organic Chemistry > Amides

Description

3,3-diphenyl-N-(1-phenylethyl)-1-propanamine is a diarylmethane.|Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.|Coronary vasodilator; inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as antiarrhythmic and antianginal agents.

Fendiline Basic Attributes

Molecular Weight：

315.45100

Exact Mass：

315.45

EC Number：

235-915-6

DSSTox ID：

DTXSID5048473

ATC Code：

C - Cardiovascular system

HScode：

2921499090

Characteristics

PSA：

12.03000

XLogP3：

5.95030

Density：

1.031g/cm3

Melting Point：

200-201

Boiling Point：

208 °C

Flash Point：

207.9ºC

Refractive Index：

1.582

Vapor Pressure：

2.3E-08mmHg at 25°C

Drug Information

MeSH：

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

MeSH Entry Terms：

Fendilin

Computed Properties

Molecular Weight:315.5
XLogP3:5.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:7
Exact Mass:315.198699802
Monoisotopic Mass:315.198699802
Topological Polar Surface Area:12
Heavy Atom Count:24
Complexity:303
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes