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Home > Encyclopedia > 1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one

1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one

1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one structure

1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one 

structure
  • CAS No:

    18125-49-0

  • Formula:

    C11H12N2O2

  • Chemical Name:

    1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one

  • Synonyms:

    3H-Pyrazol-3-one,1,2-dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-;3-Pyrazolin-5-one,3-(hydroxymethyl)-2-methyl-1-phenyl-;1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one;3-(Hydroxymethyl)-2-methyl-1-phenyl-3-pyrazolin-5-one;3-Hydroxymethylantipyrine;Hydroxymethylantipyrine;34957-05-6;65426-35-9

Description

3-hydroxymethylantipyrine is a pyrazolone that is antipyrine in which one of the hydrogens of the 5-methyl group is substituted by a hydroxymethyl group. It is a metabolite of the analgesic drug, antipyrene. It has a role as a drug metabolite and a human urinary metabolite. It derives from an antipyrine.

1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one Basic Attributes

204.22500

204.23

3F5YS569EB

DTXSID00171087

2933199090

Characteristics

47.16000

0.66830

1.265g/cm3

140 °C @ Solvent: Tetrahydrofuran

351.2ºC

166.2ºC

1.611

1.55E-05mmHg at 25°C

Drug Information

3-hydroxy-methylantipyrine is a known human metabolite of antipyrine.

3-HMAP

Computed Properties

Molecular Weight:204.22
XLogP3:-0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:204.089877630
Monoisotopic Mass:204.089877630
Topological Polar Surface Area:43.8
Heavy Atom Count:15
Complexity:282
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Guide of 1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one

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