 Home > Encyclopedia > 2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride

2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride

2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride structure

CAS No:
405940-76-3
Formula:
C24H21ClF4N8O2
Chemical Name:
2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride
Synonyms:
Razaxaban HCl; UNII-7CLJ1MEZ8V; Razaxaban Hydrochloride; DPC 906;

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Description

Razaxaban Hydrochloride is the hydrochloride salt form of razaxaban, an orally active, 1,2-benzisoxazole-containing, inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Razaxaban forms an isoxazole-ring opened, stable, benzamidine metabolite which is subsequently excreted through the bile.

2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride Basic Attributes

Molecular Weight：

564.92300

Exact Mass：

564.1412123 g/mol

UNII：

7CLJ1MEZ8V

DSSTox ID：

DTXSID10193598

NCI Thesaurus Code：

C81464

Characteristics

PSA：

124.25000

XLogP3：

5.36930

Boiling Point：

654.8ºC

Flash Point：

349.8ºC

Drug Information

MeSH Entry Terms：

1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-(2-fluoro-4-((2'-dimethylaminomethyl)imidazol-1-yl)phenyl)-1H-pyrazole-5-carboxamide

Computed Properties

Molecular Weight:564.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:6
Exact Mass:564.1412123
Monoisotopic Mass:564.1412123
Topological Polar Surface Area:120
Heavy Atom Count:39
Complexity:838
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Guide of 2-(3-amino-1,2-benzoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]imidazol-1-yl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide,hydrochloride

Description
Basic Attributes
Characteristics
Drug Information
Computed Properties

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